24^th International Conference on
Vaccine Design, Production & Safety

Ahmed Hegazi is a Professor of microbiology and immunology department in National Research Center, Egypt Work Experience • National Research Center, Dept. Zoonotic Diseases, 2004 Prof. of Microbiology & Immunology- up till now Educational Activities • Conducted training courses on Clinical Microbiology, National Research Center, 1979, 1980, 1981, 1987 • Organized training courses on Immunology, National Research Center, 1987-2002 Conducted training courses on Immunology, Faculty of Medicine, Zagazig University, • 1981-1997 • Supervised the Immunology lab, Faculty of Medicine, Zagazig University, 1981-1997

microbiology and immunology department

Bibi Razieh Hosseini Farash is affiliated to the Tehran University of Medical Sciences,

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Bibi Razieh Hosseini Farash is affiliated to the Tehran University of Medical Sciences, Iran.

Research Interest

Francis Eko is professor of Microbiology and Immunology at Morehouse School of Medicine, Atlanta (USA). His expertise is in the development of vaccines and vaccine adjuvants. Current research involves development of self-adjuvanting vaccines against Chlamydia genital and respiratory infections and the effect of VCG-based adjuvants on immune responses to mucosal and systemic vaccines.

Vaccines, Vaccine Delivery Systems and Adjuvants

Dr. Laura Hong has more than 15 years extensive experience in biologics and vaccine development. She had been support for monoclonal antibody drug development in the area of CV, ID and oncology. In recent years, her major responsibilities have been leading a group in supporting vaccine process and formulation development and release, including stability of manufactured vaccine products. She has contributed in more than ten vaccine project development, including Gardasil and Gardasil 9 vaccine

Biologics and vaccine development,.and support for monoclonal antibody drug development in the area of CV, ID and oncology.

Formal education 2002-2006 Bacheloras in Biomedicine Federal University of Pernambuco, UFPE, Recife, Brazil Title: Evaluation of single tube Nested-PCRto detect aexMycobacterium tuberculosisaea direct on blood from patientsup to 15 years of age. Supervisor: Haiana Charifker Schindler, PhD Scholarship from: National Council for Scientific and Technological Development (CNPq) 2007-2009 Master. Degree: Public Health Oswaldo Cruz Foundation Aggeu Magalhaees Research Center CPqAM/FIOCRUZ Title: Detection of Mycobacterium tuberculosis using the Single tube Nested-PCR in samples of blood and urine. Supervisor: Haiana Charifker Schindler, rKeywords: Tuberculosis; PCR; Blood; Urine. 2010-2014 Doctoradeae Degree: Ph.D. in Science Federal University Dep. of Clinic Medicine / Institute of Torax Research Title: Evaluation of technique of single tube Nested-PCR with a colorimetricdetection for the diagnosis of tuberculosis. Fellowship: Coordenaagaeo de Aperfeiagamento de Pessoal de Navel Superior Supervisor: Fernanda Carvalho de Queiroz Mello, Ph.D. Haiana Charifker Schindler, Ph.D Rafael Silva Duarte, Ph.D. Keywords: Tuberculosis; PCR; Blood; Urine, ELISA, Diagnosis.

Evaluation of a PCR-ELISA system to detect childhood TB and use of children as signaling of missing bacillipherous cases. 2. Development and Validation of Molecular and Immunologic Approaches for Children's Tuberculosis Diagnostics 3. Development, optimization and PCR evaluation system in single tube with colorimetric detection of tuberculosis through paucibacillary clinical samples. 4. Molecular and immunological tools for understanding the dynamics transmission of Leishmaniasis. 5. Development and evaluation of automatable system for colorimetric detection of TB in adults and children. 6. PCR system development for the detection of "Mycobacterium ulcerans", responsible for Buruli ulcer, direct clinics amostars (blood and urine).

Education. Pietro Mastroeni 1990. Doctor of Medicine and Surgery at the University of Messina, Italy. 1991-94. Doctor of Philosophy, Department of Pathology and Darwin College, University of Cambridge. Professional history. 1992-96. Ricercatore Universitario in Malattie Infettive (tenured Lectureship in Infectious Diseases), University of Messina, Italy. 1997. Research Associate at the University of Newcastle, Department of Microbiology, The Medical School, Newcastle upon Tyne, UK. 1997-1999. Research Fellow, Department of Biochemistry, Imperial College of Science, Technology and Medicine, University of London, UK. 1999-2004. University Lecturer in Microbiology, Department of Veterinary Medicine, University of Cambridge. 2004-2008. University Senior Lecturer in Microbiology, Department of Veterinary Medicine, University of Cambridge. Reviewing and Editorial activities Member of the Editorial Board of Microbes and Infection, The Scientific World Journal and The Canadian Journal of Infectious Diseases and Medical Microbiology. Reviewing papers for: Nature Medicine, Nature Biotechnology, Proceedings of the National Academy of Science (PNAS), Journal of Experimental Medicine, Journal of Infectious Diseases, Cell, Host and Microbe, European Journal of Immunology, Cellular Microbiology, Journal of Antimicrobial Chemotherapy, PLoS Pathogens, PLoS One, Immunology, Infection and Immunity, FEMS Immunology and Medical Microbiology, Microbiology, BioDrugs, Clinical and Experimental Immunology, Molecular Microbiology, Trends in Microbiology, Canadian Journal of Microbiology, International Immunopharmacology, Microbes and Infection, Expert Reviews in Molecular Medicine, Veterinary Research, Immunology and Cell Biology, Veterinary pathology, The International Journal of Bacteriology, Frontiers in Immunology, Journal of Medicine and Medical Science Research, Future Microbiology, mBio. Reviewing Grants for Biotechnology and Biological Sciences Research Council (BBSRC), The Wellcome Trust, Medical Research Council (MRC), European Research Council, Horserace Betting Levy Board (HBLB), World Health Organisation (WHO), Royal Society, Medical Research Scotland, Grant Agency of the Czech Republic, Swiss National Science Foundation, Foundation for Science and Technology of Portugal (FCT), Action Medical Research and British Society for Antimicrobial Chemotherapy, National Science Center, Poland.

Research interests. My research has focused on the interplay between bacterial pathogenesis and the immune system as the foundation for vaccine development and improved antibiotic therapy. I am interested in understanding how inflammation and immunity control bacterial infections and to study the genes/mechanisms that allow bacteria to evade killing by antibodies and phagocytes. I am also interested in the interaction between cellular and humoral adaptive immunity and in receptors and soluble mediators used by the immune system to control bacterial infections. I have been involved in the discovery and/or functional characterization of many bacterial virulence and/or immune-evasion genes as targets for live attenuated vaccine candidates. I have also combined traditional tools with forefront genome-wide approaches to understand bacterial adaptation to the host immune response in vivo and to discover vaccine candidates that are safer in immune-compromised individuals. My research has pioneered and used innovative multidisciplinary approaches, which combine immunology, microscopy, molecularly tagged microbial subpopulations and mathematical modeling, to study bacterial infection dynamics in vivo. This allowed my research group to unravel the impact of immunity, vaccination and antibiotics on pathogen behaviour at the single cell level. These approaches, are revolutionizing the study of many bacterial infections in vivo, are enabling scientists to move away from compartmentalized approaches and are yielding a global understanding of infection biology. I have also been involved in other research areas within infection, including the interplay between bacteria, autoimmune diseases and cancer

wudassie melak graduated from Jimma University for the doctor of medicine, two years working experience as a lecturer at Bahirdar University, served as a chief resident in internal medicine at mekelle University and now an internist working at Bahirdar university Hospital.

Internal medicine

Jagat Kanwar is an Associate Professor of Immunology & Cell Biology, and Group Leader in aeNanomedicine-Laboratory of Immunology and Molecular Biomedical Researchae at Deakin University, Australia. He did his PhD in 1993 from PGIMER, Chandigarh, India and worked as a Senior Scientist in The Auckland University, New Zealand for more than 10 years. He has a national and international reputation in investigating fundamental and applied molecular aspects of cancer and chronic inflammation. His research is also focused on miRNA, aptamer, locked nucleic acid (LNA) LNA-modified chimeric aptamers-siRNA conjugates, and immunoliposomes technology and disease targeted drug discovery. His research combines Immunology with state of the art and cutting edge techniques in Molecular Biology, Biochemistry, Nanobiotechnology and visualization to investigate the pathways in which key molecules are regulated in both normal and disease states. He designed nanocarriers for applications in vaccines, immunotherapy, and drug delivery of antigens immunostimulatory ligands to dendritic cells and subsequent stimuli to T- lymphocytes, B-lymphocytes and TH17 cells

Cancer and chronic inflammatory diseases targeted nanomedicine based drug delivery siRNA, miRNA anti-sense targeted gene nanomedicine based technology to target cancer and inflammation Drug discovery with anticancer targets for cancer cell survival, death, arrest, and repair Development of recombinant proteins and searching new immunomodulatory and anti-inflammatory bioactives, proteins and peptides for cancer and neuroprotection Development of complementary alternative medicine from the milk derived proteins including metal binding protein (Lactoferrin), and herbal preparation derived active components with a special focus on the treatment of colon and breast cancers Development of oral and intravenous administration of nanocarriers to overcome the challenging concept of drug resistance in various cancers Development of new generation safe, biodegradable, less toxic, disease targeted natural contrast materials for imaging Novel nano-medicinal based vaccines and immunotherapy Micro-fluidics and Lab-on-a-Chip devices for delivery and diagnosis

Dr. Mostafa Norizadeh Tazehkand is an Assistant Professor, Department of pharmaceutical Biotechnology, Faculty of pharmacy at Ecevit University. He has done his bachelors in molecular and Cell Biology at Tonekabon University, his masters in Biotechnology and PhD in Biotechnology at Cukurova University. He is skilled in Cloning, Molecular analysis of gene, Gene Expression (Real Time PCR), Chromosome Karyotyping, Antibacterial effect Assay, Mutation research. His research interest is towards Vaccine Production, Recombinant Protein Production, cancer study, cloning. He is editorial board member at different international journals.

Cytotoxic, Genotoxic studies; Carcinogenic studies; Drug and Chemical Toxicology studies

Filippo de Nicolellis graduated at Rome University aexLa Sapienzaae in 1986, where he specialized in Infectious Diseases in 1990. From 1995 to 2000, he worked as a Family Doctor in DoberdA del Lago/Doberdob (Gorizia) and since 2000 in Fiumicello, Udine, in Friuli Venezia Giulia, in the north-east of Italy. Since 2000, he has also been the President of the medical association aexCroce Medicaae, which deals with the organization of Health Services and Permanent Training and particularly with Primary Health Care and Emergency.

Infectious Diseases

Merita Kucuku is currently working in National Agency for Medicines and Medical Devices of Albania for safety, control and efficacy of vaccines. She was the Head of National Regulatory Authority of Vaccines & Immunobiological Products of Albania from 2006-2012. She has completed her MSc in 2006 and PhD on University of Tirana in Faculty of Natural Science Tirana Albania in 2010. She is a Member of Abortion WG for safety of the Global Alignment of Immunization Safety in Pregnancy (GAIA Project), Member of working group for case definiton-vasculitis, arranged from AIFA-Italy & Brighton Collaboration Geneva Switzerland and Member of reference group for the first five neonatal & first five obstetric case definitions related to immunization in pregnancy.

safety, control and efficacy of vaccines.

Sana G. AlAttas, is Associate Professor in Medical and Molecular Virology, Department of Biological Sciences -King Abdulaziz University,KAU Ibn Khaldun-Aramco Fellow,Center for Clean Water and Clean Energy Post-doctoral Fellow, Department of Civil and Environmental Engineering Massachusetts Institute of Technology(MIT) Educational Background 2013-2015: Postdoctoral fellow MIT (Massachusetts Institute of Technology-Boston) Department of Civil and Environmental Engineering Joined an ongoing project in Prof. Martin Polz Lab 2008: Ph.D. in Virology. Thesis entitled "Multi-technical Virological Study of Cytomegalovirus Kinetics in Immunocompetent and Immunocompromised Individuals" (KAU) Jeddah. Successfully completed 53 credit hours with a GPA (4.9/5). 2002: Masters degree in Virology. Thesis entitled "Studies on Some Locally Isolated Phages of Lactic Acid Bacteria." (KAU) Jeddah. Successfully completed 32 credit hours with a GPA (4.84/5) 1993: Bachelors degree in Microbiology. College of Sciences, King Abdul-Aziz University (KAU) Jeddah. GPA: 3.7/5 Work Experience: 2013-2015: Postdoctoral fellow MIT (Massachusetts Institute of Technology-Boston) –Joined an ongoing project in Prof. Martin Polz Lab (Molecular and bioinformatics analysis of host parasite interactions using marine phages as a model system). 2009 -2013: Teaching at KAU Jeddah in the Science Faculty (Assistant Professor) different courses (Virology 330 ,Microbiology 231 ,First Aid 200 ),in addition to supervised the Lab sections . 1999: I have worked as a lecturer at the KAU for six months at the Microbiology Department. 1992-1993: I have worked at Jeddah Regional Center during Bachelors graduate year, as i have gained a lot of experience by handling patients' samples of hepatitis (A, B, C, and Delta).

Research interests: 1- Diagnostic Molecular Virology 2- Vaccine Evaluation and Efficiency 3- Diagnostic field of human and animal viral or microbial diseases 4- Epidemiological studies of human and animal viral diseases 5- Anti-viral drugs susceptability 6- Serological studies on Host Viral interaction 7- All new ideas related to the Microbiology field & Environmental microbiology

Principal Investigator at Institut Pasteur of Shanghai (IPS), Chinese Academy of Science (CAS), and Associate Director of CAS Key Laboratory of Molecular Virology and Immunology. He had been a tenure-track Assistant (2001-2006) and Associate Professor (2007-2012) at University of Rochester, New York. He obtained a Medical Degree after completion of the 8-year Curriculum at Peking Union Medical College, Beijing China, and then a PhD degree in Viral Immunology from Open University under the tutelage of Regius Professor of Physic, Sir G.J.P. Sisson of University of Cambridge in England. He completed postdoctoral training with Drs. R. A. Koup and D. D. Ho, respectively, at the Aaron Diamond AIDS Research Center in New York. While in US, he has been a Principal Investigator or Co-investigator of over 20 research grants from NIH and The Bill & Melinda Gates Foundation. Back in China, he has been a Principal Investigator of National Key Program Project Grant of MOST, and grants from NSFC and CAS. He has served on numerous US NIH study sections, and also as international expert reviewer for research agencies of England, Netherland, Hong Kong, Taiwan and Singapore. He has served as Chair (HVTN-064, HVTN-083) and Co-Chair (HVTN-063 and HVTN-094) of phase I HIV vaccine clinical trials conducted by the HIV Vaccine Trials Network (HVTN) of NIH/NIAID. He is an Academic Editor of PLoS ONE, Editorial Board Member of JAIDS, and Associate Editor of Virologica Sinica. His laboratory works principally on HIV, dengue virus and Zika virus. Xia Jin, MD, PhD, is currently a Distinguished Professor and He has published over 80 SCI papers in academic journals such as Science, J Exp Med, J Clin Inv, J Immunol, J Virol, J Inf Dis, and Vaccine, including a highly cited one (Jin et al., J Exp. Med., 1999; 481 times, PubMed ).

Viral Disease and Vaccine Translational Research

Dr. Hailelule Aleme, have completed my MSc at the age of 29 years from Addis Ababa University School of Health Sciences. Basically, i am an instructor at Dilla University in Tropical and Infectious Diseases with assistant professor academic rank. I have published around 11 papers in reputed journals and presented more than 10 papers in national and international conferences, published in their proceedings. I have been working at different position at university level. Hailelule Aleme is an instructor in Tropical and Infectious Diseases at Dilla University, Ethiopia. His expertise is in the area Infectious diseases, food safety and Zoonoses. He is highly involved in researches related to HIV-Toxoplasmis co-infection, Toxoplasmosis in pregnant women, Toxolasmosis in animals, Retrospective and active surveillance of rabies virus, salmonella and food safety issue, brucellosis and its zoonotic importance and others. He has published original research papers in reputed journals and presented in national and international conferences.

His expertise is in the area Infectious diseases, food safety and Zoonoses. He is highly involved in researches related to HIV-Toxoplasmis co-infection, Toxoplasmosis in pregnant women, Toxolasmosis in animals, Retrospective and active surveillance of rabies virus, salmonella and food safety issue, brucellosis and its zoonotic importance and others. He has published original research papers in reputed journals and presented in national and international conferences.

Dr Jacques Choucair got his MD degree in 1994 from the Saint-Joseph University, Faculty of Medicine in Beyrouth then his ID subspeciality from Paris VII University, School of Medicine Since May 2001, he is a practitioner and ID consultant in the Infectious diseases department at Hôtel Dieu de France de Beyrouth teaching hospital. He published more than 20 articles and is a reviewer in national and international journals. His main topics of interest are bacterial resistance and the proper use of antibiotics. He is a member in the arab association for the proper use of antibiotics and member of ESCMID.

bacterial resistance and the proper use of antibiotics.

Muğla Sıtkı Koçman University Faculty of Science, Department of Molecular Biology and Genetics, Kötekli Campus 48000, Muğla, TURKEY

Department of Molecular Biology and Genetics,

mugla sitki kocman University Faculty of Science, Department of Molecular Biology and Genetics, Kötekli Campus 48000, Muğla, TURKEY

Department of Molecular Biology and Genetics

Muğla Sıtkı Koçman University Faculty of Science, Department of Molecular Biology and Genetics, Kötekli Campus 48000, Muğla, TURKEY

Department of Molecular Biology and Genetics

Muğla Sıtkı Koçman University Faculty of Science, Department of Molecular Biology and Genetics, Kötekli Campus 48000, Muğla, TURKEY

Department of Molecular Biology and Genetics, Kötekli Campus

Morgane Bomsel

MUCOSAL ENTRY OF HIV AND MUCOSAL IMMUNITY

Jorge Alberto Panameno Pineda has completed his Medical Doctorate in 1990 at Universidad Evangelica of El Salvador followed by his Internal Medicine Residency at the Salvadorian Institute of Social Security and a Master of Science in Tropical Medicine and Infectious and Parasitic Diseases at the University of Brasilia, Brazil in 1996. Currenty he is the Executive Director of the Fundación Salvadoreña para la Inmunoinfectologia y Medicina Tropical, a non-profit organization dedicated to research infectious and parasitic diseases and vaccinology. He was awarded the World Health Travel Award funded by the Bill and Melinda Gates Foundation in 2012.

Tropical Medicine and Infectious and Parasitic Diseases

Pierre A. MORGON is the Founder of MRGN Advisors. He is Chairman of the board of Virometix and he is Non-Executive Director at the boards of Theradiag and of Eurocine Vaccines. He is also Regional Partner for Switzerland at Mérieux Development. He holds a Doctorate of Pharmacy, a Master in Business Law and a MBA. He is also an alumnus of INSEAD, IMD and MCE executive programs.

Pharmaceutical, biological industry and in healthcare

Stuart Adler, M.D. is a Professor of Pediatrics, Microbiology and Medicine and Director of Infectious Diseases at the Children Medical Center, Virginia Commonwealth University Medical Center. Dr. Adler has specialized in CMV infections among women and children for over 28 years and has published extensively on this topic. Adler received his medical degree from Johns Hopkins University, and stayed to complete his residency and subspecialty training in Pediatric Infectious Diseases. He joined VCU's Department of Pediatrics in 1979 and chaired the Division of infectious Disease until 2006. Dr. Adler is one of the world's experts on congenital cytomegalovirus infection having worked in this field since 1979. He has published over 200 abstracts, research articles, reviews and book chapters on cytomegalovirus infections and is a frequent invited speaker on CMV at national and international symposium and conferences. Some of his publications relevant to CMV and pregnancy are listed below. He is available at no cost to provide informal or formal consultations regarding CMV and pregnancy. Dr. Adler and Dr. He has participated in clinical trials for vaccines and prevention of infection in daycare centers through hygienic methods and advocates universal screening of mothers and newborns

Pediatric Infectious Disease

Professor Dr. Daniel Stamboulian graduated with honors from the University of Buenos Aires, Argentina, in 1962, and obtained his specialty degree in Pediatrics in 1965. After successfully completing a postdoctoral training in infectious diseases at the University of Southern California, in 1971 he returned to his country. He is the founder of the Pan-American Association of Infectious Diseases (API), where he served as President from 1985 to 1986. Prof. Dr. Stamboulian is also a co-founder of the Argentine Society of Infectious Diseases (SADI), and was the Society’s first President (1983-1986). In 2005, he was named Emeritus Professor of Infectious Diseases at Universidad de Ciencias Empresariales y Sociales (UCES, University of Social and Entrepreneurial Sciences) and in 2008 he was appointed the rank of Voluntary Professor of Medicine at the University of Miami. Since 2010, he holds the title of Honorary Professor at Instituto Universitario CEMIC. ] Prof. Dr. Daniel Stamboulian is the founder and Chairman of the non-profit organization FUNCEI in Argentina. In 2001, he founded FIDEC (Fighting Infectious Diseases in Emerging Countries), a non-profit organization based in the United States. He has received numerous awards throughout his career. In 2010 he was granted the aeœBicentennial Medalae (2010), to a prominent member of the Armenian Community in Argentina and in recognition of his work as a medical consultant for the Ministry of Health of the City of Buenos Aires

His research interests Infectious Diseases

Monica BUTNARIU has her expertise in evaluation and passion in improving research interests are directed toward the chemistry and analytical biochemistry, the research on natural compounds/active principles of plants environment protection, the development of approaches for chemical characterization of plants/plant mixtures using different methods and Food and Nutrition Research. She published 57 papers ranked in ISI Thomson Reuters journals, The Hirsch index from Web of Science Core Collection (Clarivate Analytics) is 18, (Results found: 57, Citing Articles:157, Citing Articles without self-citations:135, Average Citations per Item:10.04, h-index:18) and the Hirsch Scopus index is 10.). A number of 4 books and 4 chapters in books were also published (Springer). The team coordinator has 5 patents: Number: RO122893-B; RO122836-B1; RO122834-B1; RO122952-B1; RO125201-A2; and RO125201-B1, from Derwent Innovations Index (Clarivate Analytics).

The research interests are directed toward the chemistry and analytical biochemistry, the research on natural compounds/active principles of plants environment protection, the development of approaches for chemical characterization of plants/plant mixtures using different methods.

Professor Noah Isakov holds the Joseph H Krupp Chair in Cancer Immunobiology at the Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, at Ben Gurion University of the Negev, in Beer Sheva, Israel. He graduated from the Weizmann Institute of Science in Rehovot, Israel (1981) and worked as a postdoctoral researcher at the University of Minnesota in Minneapolis, MN (1981-1983) and the Scripps Research Institute in La Jolla, CA (1983-1987). He performed sabbaticals at the NICHD, National Institutes of Health in Bethesda, MD (1993-1995), the Oklahoma Medical Research Foundation in Oklahoma City, OK, where he held the Esther Greenberg Honors Chair in Biomedical Research (2003-2004), and the Otago University in Dunedin, New Zealand (2015).in As, Agricultural University of Norway, Norway about animal production and statistics. He received his Dr.Sc.degree in Statistical Animal Genetics Group (Institute of Animal Sciences) from Swiss Federal Institute of Technology Zurich (ETH Zurich), Switzerland at 2006. As a part of his doctorate studies he spent 2 months in INRA Paris, France. He was a post doctoral researcher at the Roslin Institute, University of Edinburgh, Scotland, UK in Genetics and Genomics department and at the Laurentian Forestry Institute, University of Laval, Quebec, Canada in forestry genomics in 2008-2010 and 2010-2011 respectively. Currently he is an associate professor in Biometry and Genetics Section, Department of Animal Science at Akdeniz University, Turkey.

Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences

My name is Noemí González Martínez, I live in Barcelona, Spain and I am 23 years old. Since I was a child saving lives has been my motivation, that is the reason why I decided to become a microbiologist and immunologist. I developed my career in the Universitat Autònoma de Barcelona where I studied a degree in microbiology and the Universitat de Barcelona where I did my master in advanced immunology where I developed my love for the development of vaccines. I have been lucky to be able to research into the first stages of the creation of a vaccine against Leishmania infantum, the causal agent of the visceral leishmaniosis. As a microbiologist I know the double paper that microorganisms play in human health, as a part of our protective microbiota or as a pathological entities. As an immunologist, providing protection against pathological microorganisms is my objective.

Microbiology and Immunology